Welcome to the Hueschen Lab!

The Hueschen Lab studies mechanobiology: motility, cytoskeletal

organization, and cell and organismal shape. We use parasitic organisms as models

and currently focus on key physical phenomena in the lives of parasites:

locomotion, penetration of host tissue, and morphogenesis.

Overview

The Hueschen Lab studies how parasitic cells and animals move, penetrate through tissue, and change shape. We use microscopy, experimental approaches from cell and parasite biology, and physical and mathematical thinking. Current topics of interest include the dynamics and patterning of cytoskeletal proteins inside the parasitic cells that cause toxoplasmosis, mechanisms of cell gliding motility, the mechanics of tissue penetration by parasites, and the mechanics of morphogenesis (shape change).